cialis

The Truth About Cialis Side Effects & Long-Term Risks

Written by: Jack Health Team
Reviewed by: Sarah Bento-De Sousa PharmD. RPh

Cialis (Tadalafil) is an effective and generally well-tolerated treatment for erectile dysfunction (ED). But before starting this treatment, it’s important you know what to expect, including all potential Cialis side effects.

Like any medication, it comes with potential side effects and risks. More so if you take other medications or have underlying health conditions.

This article covers everything you need to know about long-term Cialis use—from its common side effects to more serious risks that can develop over time and how to manage them.

Why Do Cialis Side Effects Occur?

Cialis improves blood flow to the penis by relaxing and opening up the blood vessels. It blocks an enzyme called PDE5 (phosphodiesterase type 5) that allows for more blood to flow in when you’re sexually aroused. This helps achieve and maintain an erection.

However, it’s worth noting that how your body reacts to Cialis depends on several factors. These can include dosage, overall health, whether you’re taking other medications, and even what you eat and drink. All of these contribute to how well the medication works and why side effects can occur.

Common Side Effects of Cialis

Most Cialis side effects are mild and temporary, appearing within a few hours and subsiding as soon as the drug leaves your system. The most common side effects reported are:

  • Headaches – the increase of blood flow affects pressure in the brain
  • Flushing – a warm sensation on the face and neck due to blood vessel expansion
  • Nasal congestion – swelling in the nasal passages from increased blood flow
  • Dizziness – the drop in blood pressure can cause headaches and dizziness
  • Indigestion (Dyspepsia) – the relaxation of smooth muscles in the digestive tract can lead to indigestion or acid reflux

     

For most men, the effects last a few hours to a day but are easily managed. However, higher doses may make the side effects last longer. In such a case, consult your doctor immediately.

Serious Cialis Drug Side Effects and Risks

Although rare, some side effects can be serious and may require medical attention. Below are the serious side effects that require immediate medical attention.

  • Vision problems – sudden vision changes including blurred vision or a blue-tinted view. In rare cases, non-arteritic anterior ischemic optic neuropathy (NAION) can occur, leading to sudden vision loss.
  • Sudden hearing loss – Cialis may also result in sudden hearing loss or ringing in the ears, called tinnitus
  • Priapism – a painful erection lasting more than four hours and can lead to permanent damage if left untreated 

 

Additionally, Cialis should be taken with caution in heart patients. This is because the medication affects blood pressure and circulation. This can be dangerous for men with heart disease, high blood pressure, or those taking nitrates (commonly prescribed for chest pain).

Stop taking Cialis and seek emergency medical help if you experience:

  • Sudden vision or hearing loss
  • Severe dizziness or fainting (which may indicate dangerously low blood pressure)
  • Chest pain, irregular heartbeat, or shortness of breath
  • An erection lasting more than four hours (priapism)

 

What are the Long-term Side Effects of Cialis (Tadafil)?

Cialis is generally well tolerated with mild effects, but long-term use may carry potential risks.

A comprehensive study published in European Urology suggests that most healthy men can use Cialis long-term without serious side effects. However, regular health check-ups are recommended if you take Cialis frequently. This will help monitor blood pressure, liver function, and overall well-being.

Risk Factors

What to Know

Heart Health Concerns

Long-term use of Cialis may strain the heart and circulatory system because of frequent changes in blood pressure. 

Liver and Kidney Function

Cialis is processed by the liver and excreted through the kidneys. Long-term use may gradually impact organ function, especially for those with existing liver or kidney conditions.

Vision Changes

Prolonged use may increase the risk of sudden vision loss or NAION (non-arteritic anterior ischemic optic neuropathy).

Hearing Issues

Though further research is needed, long-term Cialis use and sudden hearing loss or tinnitus are often linked.

Potential Psychological Dependency

While not physically addictive, some men may develop a psychological reliance on Cialis for confidence, even when not medically necessary.

Cialis and Drug Interactions: What to Watch Out For

Cialis can interact with certain medications and substances, sometimes leading to unwanted side effects. While some interactions are mild, others can pose serious health risks.

Cialis can interact with nitrates (commonly used for heart conditions like angina) since both medications lower blood pressure. Combining them can cause a severe drop in blood pressure which may lead to fainting, stroke, or even heart failure.

Meanwhile, Cialis should not be combined with excessive alcohol as it may lead to weaker results than expected. It also increases side effects like dizziness and headaches, especially if you’re prone to low blood pressure. For best results, limit alcohol intake when using Cialis.

For best results, consult with your doctor and disclose all medications that you use regularly. This includes prescription drugs, over-the-counter pills, supplements, or any underlying health conditions.

Precautions to Take Before Using Cialis

Yes, Cialis may be effective for treating erectile dysfunction, but it’s not for everyone. Even if you’re healthy, dizziness or chest pain can still occur, so it’s important to take precautions.

Certain medical conditions increase the risk of side effects or complications. If you have a history of heart disease, stroke, or uncontrolled high blood pressure, it’s highly recommended you visit a doctor before using Cialis.

You may also opt for online healthcare services like Jack Health if you’d rather skip awkward face-to-face conversations. This is a discreet and convenient way to have your consultation and get your Cialis prescription.

Who Should Avoid Cialis?

Talk to your doctor if you have any of these conditions:

  • Heart disease or history of heart attack/stroke
  • High or low blood pressure
  • Liver or kidney disease
  • Retinitis pigmentosa or other vision disorders
  • Blood disorders (sickle cell anemia, leukemia)
  • Stomach ulcers or bleeding disorders

How to Prevent and Manage Side Effects of Cialis

Luckily, there are ways to minimize and manage the unwanted effects of Cialis. Use the guide below to adjust your treatment plan (if needed) for a smoother experience.

Helpful Tips

Why It Helps

Take the correct dosage

More isn’t always better. Always follow your doctor’s prescribed dose to prevent unnecessary side effects.

Avoid alcohol and excessive caffeine

Both may cause flushing of the skin. It can also worsen dizziness and low blood pressure.

Stay hydrated

Cialis can cause headaches, which may be aggravated by dehydration. Drinking plenty of water can help.

Eat a light meal
before taking Cialis

A light meal is best for faster and better Cialis absorption.

Stand up slowly

Cialis is sometimes reported to cause nausea. If you experience dizziness or lightheadedness, avoid sudden movements to prevent falls.

Monitor how
your body reacts

Cialis should be discontinued if severe reactions occur. Consult your doctor to adjust your dosage or explore alternatives.

 

Medical Guidelines for Safe Use
  • STANDARD DOSAGE
    According to the prescribing information for Cialis, the recommended starting dose for erectile dysfunction (ED) treatment is 10 mg. It can be adjusted between 5 to 20 mg based on effectiveness and tolerance. For men who prefer continuous use, 2.5 to 5 mg is the daily recommended dose.

  • PROPER STORAGE
    Keep Cialis in a cool, dry place away from direct sunlight and moisture. Store it at room temperature (15–30°C) and out of reach of children.

  • TAKE ON ITS OWN
    Avoid combining Cialis with other ED medications, as this can increase the risk of serious side effects.

Key Takeaways

  • While Cialis is an effective and FDA-approved treatment for ED, it can cause mild to serious side effects, including headaches, vision changes, and priapism.

  • Most healthy men can use Cialis long-term without serious side effects but regular health check-ups are highly recommended.

  • To minimize risks, follow dosage guidelines, avoid nitrates and alcohol, and disclose all your health-related info to your doctor.

Frequently Asked Questions

➧ How Long Do Cialis Side Effects Last?

Most common side effects, like headaches and flushing, last a few hours and typically subside as the drug leaves your system. However, effects like indigestion or muscle pain may persist for up to 48 hours. This may be due to a higher dosage or slower drug absorption.

➧ Do Cialis Side Effects Go Away?

Yes, in most cases. Mild effects like headaches and flushing improve as your body adjusts to the medication, especially with regular use. But if symptoms persist, worsen, or interfere with daily life, consult a doctor.

➧ Is it OK to Take Cialis Every Day?

Yes, but only if prescribed by a doctor. Cialis can be taken at a daily dose of 2.5 mg or 5 mg for more spontaneous experiences. Meanwhile, the as-needed dose of 10 mg or 20 mg is best taken before intercourse. If you’re unsure which option is best for you, consult a healthcare professional.

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