cialis

How Long Does Cialis Last in Your System? How Long Till It Kicks In?

Written by: Jack Health Team
Reviewed by: Sarah Bento-De Sousa PharmD. RPh

Cialis (tadalafil) is a widely used medication for the treatment of erectile dysfunction (ED). As a PDE5 inhibitor, it helps increase blood flow to the penis, improving erections when combined with sexual arousal. But how long does Cialis last in your body?

The effects of Cialis can remain active in your body for up to 36 hours with the 20 mg dose. Knowing its onset time and how it interacts with your body can help you plan when to take it for optimal results.

If you’re planning to take Cialis, Jack Health offers discreet access to Cialis through online consultations and delivery for a seamless experience.

The “Weekend Pill” Explained

One of the primary reasons people choose Cialis is its long duration of action. Unlike Viagra (which lasts up to 4 hours) or Levitra (lasting up to 8-10 hours), Cialis works for up to 36 hours when taken in a 20 mg dose

The long duration of Cialis gives you the flexibility to enjoy sexual activity without worrying about precise timing. This makes it especially appealing to Canadian men who value spontaneity.

What is the Half-Life of Cialis?

The half-life of Cialis is approximately 17.5 hours. After 17.5 hours, half of the Cialis dose remains in your body, while the other half is metabolised and eliminated.

Implications for Users

Cialis should not be taken more frequently than once every 24 hours. Overuse can lead to unwanted side effects like flushing, headaches, dizziness, and indigestion. Space out your doses to ensure that you do not exceed the recommended dosage.

Cialis can also interact with medications used to treat high blood pressure or heart disease. If you have underlying heart problems, consult with a healthcare provider before using Cialis. Cialis should not be combined with nitrates, as this can lead to a dangerous drop in blood pressure.

How Does Tadalafil (Cialis) Dosage Affect Duration?

Cialis is available in both daily and on-demand dosages. The dosage pattern of Cialis you take can impact how long the medication remains effective.

Daily dosages (2.5 mg and 5 mg)

The Cialis 5 mg dosage is approved for daily use. When taken daily, the duration of action remains active as long as you continue taking it. This option is ideal for men who engage in sexual activity frequently (three or more times a week) and prefer spontaneous intimacy.

Read more about the benefits of taking Cialis daily.

10 mg dosage (as needed)

The 10 mg dose is designed for occasional use. It provides effectiveness for up to 36 hours, with most men experiencing full effects after 30 minutes of intake. This dosage is ideal for individuals seeking a consistent window of effectiveness without the need for daily medication.

20 mg dosage (as needed)

If you have not seen success with the 10 mg dosage or require a stronger effect, the 20 mg dose can provide the same duration of action as the 10 mg for up to 36 hours. Effects also begin working after 30 minutes.

 

Dose

Type

How Long It Lasts

How Long It Takes to Work

Best For

2.5 mg or 5mg

Daily dose

Works continuously as long as it is taken daily

No waiting; stays active in your system

People who have sex frequently

10 mg

On-demand dosing

Up to 36 hours

30 minutes 

Occasional use; for people who want flexibility without needing to take a pill every day

20 mg

On-demand dosing

Up to 36 hours

30 minutes 

Those needing a stronger effect or who haven’t had success with the 10 mg dose


If you’re looking to enhance your sexual performance, check out: Does Cialis make you bigger?

How Long Until Cialis Kicks In?

Cialis takes effect within 30 minutes after intake. However, the time it takes for Cialis to take effect can be influenced by lifestyle factors.

Factors Influencing the Onset of Cialis in Your System

Be wary of the following, especially when you’re on a weekend getaway or spontaneous nights out:

  • Food and Meal Interaction: Taking Cialis on an empty stomach allows it to be absorbed more quickly, whereas a heavy meal may slow its onset.
  • Alcohol Sensitivity: Excessive alcohol intake can interfere with Cialis’s effectiveness and may decrease the ability to attain an erection.

 

Cialis vs. Other ED Medications

The main difference between Cialis and other ED medications lies in their duration of action. 

Cialis vs. Viagra

Cialis lasts much longer, up to 36 hours, while drugs like Viagra work for up to 4 hours. This longer duration makes Cialis more suitable for men seeking spontaneous intimacy. Viagra suits planned sexual activity.

Cialis vs. Levitra vs. Stendra

Cialis also lasts much longer than Levitra, which can only last for up to 8-10 hours, compared to Cialis’s 36-hour efficacy. Stendra, on the other hand, is not available in Canada. Health Canada has not approved Stendra, and it is not authorised for sale in the country.

When to Consult a Healthcare Provider

Cialis is a prescription medicine. Consult your doctor or Jack Health for a discreet Canadian telehealth consultation to ensure it’s the right treatment for you and to receive professional guidance tailored to your needs.

Get Cialis treatment today.

Persistent or Worsening ED Symptoms

Cialis prolongs sexual performance and relieves erectile dysfunction. If you believe the treatment is not helping with ED at all, consult your doctor for medical guidance on adjusting your treatment.

Side Effects or Adverse Reactions

If you’re taking Cialis daily, make sure to take this medication at the same time every day or with more than a 24-hour gap to avoid potential overdose and side effects

Side effects can also be experienced by those taking the 10 mg and 20 mg dosages.

  • Common side effects: headache, indigestion, back pain, muscle aches, nasal congestion, facial flushing
  • Uncommon side effects: swelling of eyelids, eye pain, red eyes, dizziness, allergic reaction
  • Rare side effects: priapism (prolonged erection), chest pain, vision loss, hearing loss, transient amnesia

 

Stop taking Cialis and call your doctor immediately if you experience severe side effects. If you’re having a prolonged erection lasting more than 4 hours, this may result in permanent penile tissue damage and erectile dysfunction.

Key Takeaways

  •  Cialis lasts up to 36 hours and is ideal for men seeking sexual spontaneity.
  • The onset time of Cialis is typically 30 minutes after intake.
  • Always consult a healthcare provider before starting Cialis.

 

Frequently Asked Questions

Can lifestyle changes improve Cialis effectiveness?

Yes, lifestyle changes like regular exercise (e.g., winter activities), a balanced diet, and limiting alcohol intake can enhance Cialis effectiveness by supporting overall health and circulation.

Is generic tadalafil as effective as Cialis in Canada?

Yes, generic tadalafil is bioequivalent to Cialis and is approved by Health Canada for treating ED. Both drugs offer the same effectiveness.

What should I do if Cialis doesn’t work?

Clialis only works when you’re sexually stimulated. If Cialis doesn’t work, consult a healthcare provider for possible dosage adjustments or alternative treatments.

Can I take 20 mg of Cialis two days in a row?

Yes. You can take 20 mg of Cialis twice in a row, provided that you wait at least 24 hours between doses to avoid side effects and ensure safety.

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