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minoxidil

Minoxidil Vs Nanoxidil Vs Hello Hair Solutions | Jack Health

Minoxidil, Nanoxidi, and Hello Hair Solutions are products that stand out as hair loss treatments due to their track records of success. These treatments are helping people with advanced patterns of baldness as well as those who are just beginning to experience hair thinning.
Written by: Jack Health Team
Reviewed by: Sarah Bento-De Sousa PharmD. RPh

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Minoxidil, Nanoxidi, and Hello Hair Solutions are products that stand out as hair loss treatments due to their track records of success. 

These treatments are helping people with advanced patterns of baldness as well as those who are just beginning to experience hair thinning. 

This article will thoroughly review Minoxidil, Nanoxidil, and Hello Hair Solutions to help health-conscious individuals make informed decisions.

Differences Between Minoxidil and Nanoxidil

Nanoxidil has one less carbon chain and two fewer hydrogen atoms than Minoxidil. As a result, Nanoxidil has fewer adverse effects and is better absorbed into the scalp. Only 1.4% of Minoxidil is absorbed through the scalp.

In the following subsections, we will explore various aspects of Minoxidil and Nanoxidil, such as their effectiveness, ease of use, side effects, and cost and accessibility.

Effectiveness

Minoxidil has been helping individuals combat hair loss for over 30 years. 

Minoxidil increases blood flow to hair follicles, encourages thicker and fuller hair, helps regrow hair in balding regions, and prolongs the anagen phase.

Nanoxidil, formulated by DS Laboratories, represents improved Minoxidil with potentially fewer side effects. 

Spectral. DNC-N®  (Nanoxidil) formulation also includes:

  • Copper peptides for improved vascularization and reduced inflammation;
  • Retinol for preventing pattern baldness;
  • Olamine due to antibacterial and antifungal action;
  • The most recent nanosome encapsulation technology for improved absorption at the hair follicle base.

 

A study evaluating Spectral DNC-N®’s effectiveness and tolerability showed that hair loss decreased after three months of treatment, and hair mass and density increased.

Ease of Use

Typically, Minoxidil comes with patient instructions and the dermatologist’s recommended dosage. It should be applied two times a day (topical solution or foam). Minoxidil should be gently massaged into the scalp and left to completely dry for 2 to 4 hours.

Nanoxidil should be used daily for optimal results. It is advised to apply 1 milliliter twice daily to the hair loss area and leave it on for at least four hours before washing hair.

Side Effects

A few minor side effects have been reported in the studies determining Nanoxidil’s efficacy and safety profile: 

  • Skin/scalp irritation
  • Skin dryness
  • Mild to moderate skin redness
  • Oiliness.

 

Long-term studies on Nanoxidil’s safety have yet to be conducted.

Minoxidil’s known side effects include:

  • Skin/scalp irritation
  • Allergic contact dermatitis
  • Hair shedding
  • Changes in hair color.

 

Minoxidil is safe to use with other treatments, such as Finasteride.

Cost and Accessibility

Prices for Minoxidil solution can range from CAD 32 to CAD 100, depending on the brand, concentration, and size of the product. Generic versions of Minoxidil are cheaper than the brand-name versions.

The price of Nanoxidil in Canada is approximately CAD 40/month or CAD 98/three-month supply.

How Does Hello Hair Compare to Minoxidil and Nanoxidil?

Hello Hair solution by Jack.Health contains 5% Minoxidil, 0.1% Finasteride, and 0.03% Latanoprost. 

It targets various causes of hair loss.

Latanoprost, a prostaglandin (PG) F2𝛼 analog used to treat glaucoma, is effective for treating various types of alopecia. 

Finasteride is a prescription medication that targets the hormonal cause of hair loss. Usually, Finasteride takes three to six months to start working, whereas Minoxidil alone takes eight to sixteen weeks. It takes about 24 weeks for Latanoprost to begin working. 

Twenty-three participants with androgenic alopecia who used Hello Hair saw 100% hair regrowth, and 82% saw notable increases in hair density throughout a 6-week study.

The price for Hello Hair is $320/2 months or $480/4 months.

Which Hair Regrowth Solution Should You Choose?

The hair type, degree of hair loss, and individual medical conditions influence the choice of hair loss product. 

Early stages of thinning might respond well to Minoxidil or Nanoxidil alone. 

Because Hello Hair targets multiple causes of hair loss, it is the best option for advanced hair loss.

Key Takeaways

  • Minoxidil is a long-standing treatment that increases follicular blood flow and encourages hair growth. Nanoxidil, a DS Laboratories invention, offers a formula similar but possibly less irritating to Minoxidil. 
  • Hello Hair Solutions combines Minoxidil with Finasteride and Latanoprost, targeting hair loss from multiple angles. 
  • While these treatments have proven effective, they come with potential side effects ranging from scalp irritation to changes in hair color.

Frequently Asked Questions

Are There Fewer Side Effects with Nanoxidil Than Minoxidil?

Nanoxidil has significantly fewer side effects, so switching to Nanoxidil is an excellent choice for those experiencing Minoxidil side effects.

Can Hello Hair Solutions Regrow Hair Like Minoxidil?

Individual components of Hello Hair have been demonstrated to promote hair growth, and when combined, they increase the effectiveness of Minoxidil treatment. Hello Hair contains two powerful hair growth factors that complement Minoxidil’s effects.

Is Nanoxidil Worth Trying Over Minoxidil?

Because it stimulates hair growth similarly and has fewer side effects, Spectral DNC-N® with 5% Nanoxodil is a good substitute for lotions containing 2% or 5% Minoxidil. 

Sources:

Minoxidil

Nanoxidil

Suchonwanit P, Thammarucha S, Leerunyakul K. Minoxidil and its use in hair disorders: a review. Drug Des Devel Ther. 2019 Aug 9;13:2777-2786. doi: 10.2147/DDDT.S214907. Erratum in: Drug Des Devel Ther. 2020 Feb 10;14:575. doi: 10.2147/DDDT.S247601.  PMID: 31496654; PMCID: PMC6691938.

Vincenzi C, Marisaldi B, Tosti A, Patel B. Effects of a New Topical Treatment Containing Several Hair Growth Promoters in Women with Early Female Pattern Hair Loss. Skin Appendage Disord. 2019 Apr;5(3):146-151. doi: 10.1159/000493200. Epub 2018 Oct 10. PMID: 31049335; PMCID: PMC6489052.

Buhl, A. E., Conrad, S. J., Waldon, D. J., & Brunden, M. N. (1993). Potassium channel conductance as a control mechanism in hair follicles. The Journal of investigative dermatology, 101(1 Suppl), 148S–152S. https://doi.org/10.1111/1523-1747.ep12363290

Patel, Brijesh & Velasco, Maria & Tamez, Fernando. (2016). Phase II Study to Evaluate Efficacy and Safety of SPECTRAL.DNC-N Topical Solution For the Treatment of Mild to Moderate Androgenic Alopecia. 

Spectral.DNC-N Study – Males With Thinning Hair & Alopecia (Product Efficacy)

Latanoprost

Jiang S, Hao Z, Qi W, Wang Z, Zhou M, Guo N. The efficacy of topical prostaglandin analogs for hair loss: A systematic review and meta-analysis. Front Med (Lausanne). 2023 Mar 14;10:1130623. doi: 10.3389/fmed.2023.1130623. PMID: 36999072; PMCID: PMC10043424.

Blume-Peytavi U, Lönnfors S, Hillmann K, Garcia Bartels N. A randomized double-blind placebo-controlled pilot study to assess the efficacy of a 24-week topical treatment by latanoprost 0.1% on hair growth and pigmentation in healthy volunteers with androgenetic alopecia. J Am Acad Dermatol. 2012 May;66(5):794-800. doi: 10.1016/j.jaad.2011.05.026. Epub 2011 Aug 27. PMID: 21875758.

Chandrashekar BS, Nandhini T, Vasanth V, Sriram R, Navale S. Topical minoxidil fortified with finasteride: An account of maintenance of hair density after replacing oral finasteride. Indian Dermatol Online J. 2015 Jan-Feb;6(1):17-20. doi: 10.4103/2229-5178.148925. PMID: 25657911; PMCID: PMC4314881.

Mysore V. Finasteride and sexual side effects. Indian Dermatol Online J. 2012 Jan;3(1):62-5. doi: 10.4103/2229-5178.93496. PMID: 23130269; PMCID: PMC3481923.

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