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Testosterone Gel: Uses and Side Effects

Written by: Jack Health Team
Reviewed by: Sarah Bento-De Sousa PharmD. RPh

Testosterone gel has emerged as a significant advancement in hormone replacement therapy, particularly for those grappling with the challenges of low testosterone levels. This topical medication offers a unique approach to boosting testosterone in a manner that’s both effective and minimally invasive, making it an appealing option for many. 

However, like any medical treatment, it comes with its own set of considerations, including potential side effects and specific usage guidelines. 

In this comprehensive guide, we delve into the uses of testosterone gel, exploring its benefits for enhancing physical and mental well-being, while also addressing the side effects that users should be mindful of. 

Whether you’re considering testosterone therapy for yourself or seeking information for someone else, understanding both the advantages and the precautions is key to making an informed decision.

What is Testosterone Gel?

Testosterone gel is a medication prescribed to men and women who are experiencing low testosterone levels. This condition, often referred to as testosterone deficiency, can lead to various symptoms such as reduced sex drive, fatigue, and mood changes. The gel is applied directly to the skin, allowing testosterone to be absorbed into the body and help regulate hormone levels.

How Does Testosterone Gel Work?

Testosterone gel works by being applied to the skin, typically on the abdomen or arms, where it can be absorbed directly into the bloodstream. This application method helps maintain steady testosterone levels in the body, improving the symptoms of testosterone deficiency.

Testosterone gel operates by delivering testosterone directly through the skin into the bloodstream, offering a straightforward method to counterbalance low testosterone levels. When applied to designated areas of the skin, such as the abdomen or upper arms, the gel facilitates the steady absorption of testosterone, thereby helping to stabilize hormone levels throughout the day. 

This method of administration not only bypasses the digestive system, potentially reducing the risk of liver-related side effects associated with oral medications but also allows for more consistent control over hormone levels, aiming to alleviate symptoms of testosterone deficiency effectively.

Testosterone Gel Facts

Common Brands

AndroGel 1%, Taro Pharmaceuticals Inc, Testim

Drug Class

Testosterone Replacement

Controlled Substance Classification

Schedule III

Generic Status

Lower-cost generic available

Availability 

Prescription Only


Testim gel stands out as another popular choice for testosterone replacement therapy, known for its unique formulation and application benefits. For a deeper dive into what makes Testim a preferred option for many, explore our comprehensive overview of Testim gel and see if it aligns with your therapy goals.

Benefits of Using Testosterone Gel

The use of testosterone gel offers a plethora of benefits for individuals experiencing low testosterone levels, profoundly impacting both physical and psychological well-being.

Increased Sexual Desire & Libido

One of the most notable benefits of testosterone gel is the improvement in sex drive and libido among men and women with low testosterone levels.

Improved Muscle Mass & Strength

Testosterone gel can also help increase muscle mass and strength, making it a valuable part of a treatment plan for those looking to improve their physical health.

Reduced Body Fat Percentage

Additionally, testosterone gel can assist in reducing body fat percentage, contributing to a healthier body composition.

Application and Dosage

The application and dosage of testosterone gel are critical factors for ensuring its effectiveness and minimizing potential side effects. Adjustments to the dosage may be made based on the patient’s ongoing assessment and blood test results to ensure optimal outcomes.

Instructions for Application

This medication is strictly for topical application and should not be ingested. Ensure you wash your hands both before and after applying it. Follow the instructions on the prescription label carefully, applying the medication at the same time each day without exceeding the recommended frequency. It’s important to use your product as intended. 

After applying, let the skin dry naturally before covering it with clothes to avoid transferring the medication to others.

Detailed USAGE INSTRUCTIONS accompany this medication. For guidance on how to properly use this medication, consult your pharmacist. Make sure to read all provided information thoroughly and don’t hesitate to discuss any queries with your pharmacist or healthcare team.

With each new prescription and refill, your pharmacist will provide a MedGuide. It’s crucial to read this document carefully every time to stay informed.

If you have concerns about using this medication with children, please consult your healthcare provider as they may require special attention.

In case of suspected overdose, immediately contact a poison control center or seek emergency medical attention.

Remember, this medication is personalized for your use only; sharing it with others is not advised.

Recommended Dosages and Frequency

The appropriate dosage of this medication can vary significantly among patients, so it’s essential to adhere to your doctor’s instructions or the guidelines provided on the medication label. The dosage information here represents average amounts, and your specific dosage may differ. Only adjust your dosage if advised by your doctor.

The dosage you require will depend on the medication’s strength. Additionally, the frequency of your doses, the interval between them, and the duration of the treatment are based on the specific health issue being addressed.

For hormone replacement therapy using a topical gel form:

Adults:

  • AndroGel® 1%: Initially, apply 50 milligrams (mg) (either two 25 mg packets or a single 50 mg packet) to clean, dry, and unbroken skin once daily, typically in the morning. Your doctor may increase this dosage if necessary, but it generally does not exceed 100 mg per day.
  • AndroGel® 1.62%: Start with a 40.5 mg application (either two pumps or a single 40.5 mg packet) to the skin once daily, preferably in the morning. Your doctor can modify this amount as required, up to a maximum of 81 mg per day.
  • Fortesta®: Begin with a 40 mg application (four pumps) to the skin once daily, usually in the morning. Dosage adjustments may be made by your doctor but typically will not exceed 70 mg per day.
  • Vogelxo™: Initially, apply 50 mg (one tube, one packet, or four pumps) to the skin daily, often in the morning. Your doctor may change this dosage as necessary, up to a maximum of 100 mg daily.

 

For children, both the usage and dosage should be determined by a doctor.

When using a topical solution form:

Adults: Start with a 60 mg application (one pump or one twist actuation of 30 mg) to each clean, dry, and intact underarm skin area once daily, typically in the morning. Your doctor may adjust your dose as needed.

For children, usage and dosage must be set by a doctor.

What to Do If You Miss a Dose

If you forget to take a dose, apply it as soon as you remember. However, if your next scheduled dose is near, skip the missed dose and proceed with your regular dosing schedule. Avoid applying extra or double doses to make up for the missed one.

What Could Interact with This Medication?

  • Diabetes medications
  • Blood clot prevention or treatment medications, such as warfarin
  • Steroids like prednisone or cortisone

 

This overview might not cover all potential interactions. It’s important to provide your healthcare provider with a comprehensive list of everything you take, including prescription drugs, over-the-counter medicines, herbal products, and dietary supplements. Also, inform them about your smoking, drinking, and any illegal drug use, as these can affect how your medication works.

Why Use Testosterone Gels Over Oral Pills?

Testosterone gels offer a way to avoid the risks associated with oral testosterone supplements, such as liver damage. Gels allow for direct absorption into the bloodstream, providing a more consistent hormone level.

Potential Side Effects of Using Testosterone Gel

Using testosterone gel can lead to a range of potential side effects, reflecting the body’s response to altered hormone levels. It’s crucial for individuals to monitor their health closely and consult their healthcare provider about any adverse effects, ensuring adjustments can be made to the treatment plan as necessary.

Acne Breakouts & Oily Skin

Testosterone gel can lead to skin-related side effects such as acne and oily skin due to changes in hormone levels.

Increased Hair Growth on the Face and Body

Some people may experience increased hair growth on their face and body as an effect of testosterone gel.

Weight Gain

Weight gain is another possible side effect, although adjusting the dosage can often mitigate this issue.

Abdominal Pain

Patients should be aware of the risk of abdominal pain and consult their doctor if they experience any problems.

While considering the benefits of testosterone therapy, it’s equally important to assess the financial implications. For those interested in AndroGel, one of the leading testosterone gels, understanding the associated costs can help in planning your treatment journey. Learn more about the cost of AndroGel to gauge the financial aspect of your therapy.

Choosing the right form of testosterone therapy is crucial to achieving your treatment objectives and lifestyle compatibility. Between gels and injections, each has its pros and cons. If you’re weighing these options, our detailed comparison on the difference between testosterone gel and injection can offer valuable insights to inform your decision.

Key Takeaways

  • Testosterone gel is a pivotal advancement in hormone replacement therapy, offering an efficient and less invasive method to manage low testosterone levels. Its application directly to the skin facilitates consistent hormone absorption, presenting a viable solution for those seeking to enhance both their physical and mental health.
  • Adhering to prescribed application and dosage instructions is crucial for maximizing the benefits of testosterone gel while minimizing potential side effects. The dosage varies among individuals, emphasizing the importance of following medical advice tailored to one’s specific health needs.
  • The benefits of testosterone gel extend beyond just addressing low testosterone symptoms, including improvements in sexual desire, muscle mass, and body fat composition. These advantages underscore the gel’s role in enhancing overall quality of life for individuals facing hormone deficiencies.
  • Awareness and management of potential side effects are essential for users of testosterone gel. While the gel offers a preferable alternative to oral testosterone supplements by avoiding liver damage risks, users must stay vigilant about skin reactions, mood changes, and other health indicators to adjust treatment as necessary.

Frequently Asked Questions

Do You Need a Prescription for Testosterone in Canada?

Anabolic steroid medicines include testosterone cypionate (such as Depo-testosterone) and testosterone undecylenate (such as Andriol). In Canada, you need a prescription to get any anabolic steroid. Illegal anabolic steroids are those that people get without a doctor’s prescription.

Where Should I Keep the Medication?

Store this medication away from children and pets to prevent misuse. Secure it to deter theft and never share it, as distribution is illegal and unsafe. Keep it at 20-25°C (68-77°F), tightly closed, and shielded from heat and light due to its flammability. Avoid heat sources and smoking near it. Dispose of any expired medication.

Does Testosterone Gel Have a Risk of Addiction?

Yes, especially when misused. Testosterone gel is a controlled substance because it has a risk of misuse, addiction, and dependency. Misuse is when the medication is taken for reasons other than prescribed. 

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